Uncovering Treatments for Addiction and Depression with GPU-Accelerated Supercomputing

A team lead by Cornell University researchers are using the Titan Supercomputer at Oak Ridge National Laboratory to study mechanisms of sodium-powered transporters in cell-to-cell communications.

Harel Weinstein’s lab at the Weill Cornell Medical College of Cornell University have constructed complex 3D molecular models of a specific family of neurotransmitter transporters called neurotransmitter sodium symporters (NSS) and simulated their actions and interactions using the NVIDIA Tesla-accelerated supercomputer. These models will help uncover potential strategies for treating behaviors such as addiction, depression, and disease-related mutations associated with disorders of the NSS proteins.

To maximize the use of their time on Titan, the researchers used the molecular dynamics application ACEMD, a highly optimized molecular dynamics software built for GPUs.


“Titan gave us a very large number of GPUs, which we could run for a very long time. Without this, our project just couldn’t work,” Weinstein said.


About Brad Nemire

Brad Nemire
Brad Nemire is on the Developer Marketing team and loves reading about all of the fascinating research being done by developers using NVIDIA GPUs. Reach out to Brad on Twitter @BradNemire and let him know how you’re using GPUs to accelerate your research. Brad graduated from San Diego State University and currently resides in San Jose, CA. Follow @BradNemire on Twitter